The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Therapeutic: laxatives. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation 1.Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass 6.Docusate … However, many people have no side effects or only have minor side effects. Inform your doctor if your condition persists or worsens. Do not share this medication with others. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. ATC Classification A06AA02 - docusate sodium ; Belongs to the class of softeners, emollients laxatives. Although only useful as a single agent in mild to moderate constipation, it can be used in conjunction with other agents in cases of refractory constipation. daily until bowel movements are normal. docusate (dok-yoo-sate) docusate calcium. Docusate is not systemically absorbed. Follow all directions on the product package unless otherwise directed by your doctor. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Despite these data, the use of saline is still considered to be first-line [McCarter 2007]. Docusate sodium should only be used for a short time. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, How Chronic Constipation Affects Your Body, Finding a Future Free of Chronic Constipation. Classification Results usually occurs 1 to 3 days after the first dose. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 1% to 10%: Respiratory: Throat irritation (liquid). Tell your doctor right away if this unlikely but serious side effect occurs: rectal bleeding. Sennosides are glucosides of rhein, and the sennosides are essentially undetectable in human milk. Certain drugs may bring about constipation and this medication acts as a stool softener. If rectal bleeding is experienced, it is typically recommended that the person seek medical attention as soon as possible. "stool softener= docusate sodium or docusate calcium?" This product may contain inactive ingredients, which can cause allergic reactions or other problems. Docusate is often used when straining to have a bowel movement should be avoided (e.g., after a heart attack or surgery). Select one or more newsletters to continue. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Selected from data included with permission and copyrighted by First Databank, Inc. daily. Classification. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you receive from the healthcare provider. Do not start, stop, or change the dosage of any medicines without your doctor's approval. In Canada - Call your doctor for medical advice about side effects. This medication should be used only when clearly needed during pregnancy. The dosage is based on your medical condition and response to therapy. Copyright(c) 2020 First Databank, Inc. How frequently do you purchase this product? Docusate sodium is a stool softener often used as the initial treatment for chronic constipation, and it is FDA approved for this purpose. Stool softeners may be used for the treatment of hemorrhoids (Shin 2015). Do not use this product for more than 1 week unless directed by your doctor. The lowest GoodRx price for the most common version of docusate sodium is around $2.56, 41% off the average retail price of $4.37. Docusate's onset of action is 6-72 hours orally and 2-15 minutes rectally 6 , 7 . This limited summary does NOT include all information available about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. How the Medication Works . Talk to your doctor if you have questions. docusate sodium. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Data from a small, prospective, randomized, double-blind controlled study comparing the intra-aural use of docusate to triethanolamine polypeptide (not available in the US) and subsequent irrigation with lukewarm normal saline as needed supports the use of docusate intra-aurally as a ceruminolytic [Singer 2000]. Use this medication only when needed. Constipation (occasional), treatment; stool softener: Children 2 years to <12 years: 50 to 150 mg/day in single or divided doses, Children ≥12 years and Adolescents: 50 to 360 mg/day in single or divided doses, Weight-directed dosing: Infants and Children: 5 mg/kg/day in 1 to 4 divided doses (Nelson 1996), Infants ≥6 months and Children <2 years: 12.5 mg 3 times daily (NICE 2010), Children ≥2 and Adolescents: 40 to 150 mg/day in 1 to 4 divided doses (Kliegman 2011); in children ≥12 years and adolescents, doses up to 500 mg/day divided may be used (NICE 2010), Children ≥12 years and Adolescents: 283 mg/5mL: 283 mg (1 unit) 1 to 3 times daily, Docusate calcium: Children ≥12 years and Adolescents: 240 mg once daily. 1. Before taking this medication, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. Physical hazards. Proprietary names - Dioctyl (capsules). If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Liquid: 150 mg/15 ml. Mix docusate liquid (50 mg per 5 mL) with milk or fruit juice to prevent throat irritation. DOCUSATE SODIUM- docusate sodium capsule, liquid filled J.P. BUSINESS ENTERPRISE Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. Docusate Sodium Oral is a medication used for treating constipation. Protect from freezing, heat humidity, and light. It is used to treat and prevent occasional constipation due to hard stools. Irritated throat (with liquid or syrup forms) may also occur. Oral: 50 to 400 mg (using any of the salt forms) orally administered in 1 to 4 equally divided doses each day. ; Usual Pediatric Dose for Constipation DC Softgels, Dioctocal, Pro-Cal-Sof, Sulfolax, Surfak. Drug interactions may change how your medications work or increase your risk for serious side effects. • Benzyl alcohol and derivatives: Some dosage forms may contain sodium benzoate/benzoic acid; benzoic acid (benzoate) is a metabolite of benzyl alcohol; large amounts of benzyl alcohol (≥99 mg/kg/day) have been associated with a potentially fatal toxicity (“gasping syndrome”) in neonates; the “gasping syndrome” consists of metabolic acidosis, respiratory distress, gasping respirations, CNS dysfunction (including convulsions, intracranial hemorrhage), hypotension and cardiovascular collapse (AAP 1997; CDC 1982); some data suggests that benzoate displaces bilirubin. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. For relief of occasional constipation. Docusate sodium Safety Data Sheet Safety Data Sheet in accordance with regulation (EC) No 1907/2006, as amended. Max: 500 mg/day. Discard after administration. Did you or will you purchase this product in-store or online? Docusate sodium: 50 to 360 mg once daily or in divided doses, Rectal: 283 mg per 5 mL: 283 mg (1 enema) 1 to 3 times daily, Ceruminolytic (off-label use): Intra-aural: Administer 1 mL of docusate sodium in 2 mL syringes; if no clearance in 15 minutes, irrigate with 50 or 100 mL lukewarm normal saline (Singer 2000). < 2 years of age: Safety and efficacy have not been established; however, 40 mg/day PO of docusate sodium has been used. Dioctyl Calcium Sulfosuccinate 2. US residents can call their local poison control center at 1-800-222-1222. If you are using the liquid form of this medication, measure the dose carefully using a special measuring device/spoon. Docusate dosage Usual Adult Dose for Constipation. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. Docusate sodium works by increasing the amount of water in the stool, making stools softer and easier to pass. Docusate sodium 100 mg is expected to produce a bowel movement within 12 to 72 hours (See Reference 2). This document does not contain all possible drug interactions. Adult : PO Constipation 50-300 mg/day in divided doses. For Child 2–11 years. Some medications and conditions can make constipation more likely. We comply with the HONcode standard for trustworthy health information -. Docusate sodium: 50-300 mg PO once daily or divided doses; Docusate calcium: 240 mg PO qDay; Rectal. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. https://www.webmd.com/drugs/2/drug-323/docusate-sodium-oral/details Tablets: 100 mg Use your next dose at the regular time. This is because your bowel can start to rely on this type of laxative to make it work rather than working on its own. Oral: Administer as a single daily dose or in divided doses; ensure adequate fluid intake. Bowel evacuation As adjunct to abdominal radiological procedures: 400 mg given w/ barium meal.Otic Softening of ear wax As 0.5% drops: Apply sufficient amount to fill the affected ear(s) on not more than 2 consecutive nights, before syringing if needed.Rectal Constipation As 283 mg/5 mL enema: 1 enema 1-3 times/day. Consumer Information Use and Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. 2. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. 1. Discuss the risks and benefits with your doctor. docusate sodium Adults and children age 12 and older: 50 to 200 mg P.O. © 2005 - 2019 WebMD LLC. DOSS 7. This stool softener works by adding to the water the stool absorbs. It usually starts to work within 1 to 3 days, but it may take up to 5 days to work. Medically reviewed by Drugs.com. Do not use a household spoon because you may not get the correct dose. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. 4 (Oral), H302 Full text of H-statements: see section 16 3.2. Capsules: 50 mg, 100 mg, 250 mg. Docusate(Cellubril) generic is a stool softener, prescribed for constipation. Docusate sodium is an ingredient in medical products such as laxatives and stool softeners. Treatment of constipation in pregnant women is similar to that of nonpregnant patients and medications may be used when diet and lifestyle modifications are not effective. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Do not double the dose to catch up. Docusate, also known as docusate salts or dioctyl sulfosuccinate, prevents/relieves dry hard stool and thus is used to treat constipation. Discontinue use and notify health care provider if rash around the anus/rectal irritation occurs or if resistance is encountered with insertion; forcing the tube may result in injury or damage to the rectum. Colace, which is docusate sodium 100 mg (References 2, 3), is a stool softener which allows water and fats in to the stool to help soften material (Reference 5) and prevent dry, hard stools. Rectal: For rectal use only. This is not a complete list of possible side effects. Docusate Sodium is the sodium salt of docusate, a dioctyl salt and an emollient laxative with stool-softening activity. Mixtures Capsules (soft gels): 100 mg, 250 mg. Where did you or where do you plan to purchase? 2 to 11 years: 150 mg/day PO for docusate sodium; 283 mg/day PR for docusate sodium. Available for Android and iOS devices. Agents other than docusate are recommended in pregnancy (Body 2016). Although it may take a day or so for the capsules/liquid to start working, if you are still constipated after five days, you should make an appointment to speak with your doctor. Decrease your dose or stop taking this medication if you develop diarrhea. You may report side effects to Health Canada at 1-866-234-2345. Alternative: 50 to 100 mg (docusate sodium liquid) added to a retention or flushing enema once a day. It works by increasing the amount of water into the bowel, which softens the stools. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Rectal: Periodic rectal exams are recommended in patients with impaired rectal function, especially loss of sensation. 12.5 mg 3 times a day, adjusted according to response, use paediatric oral solution. Some products that may interact with this drug include: mineral oil, drugs containing phenolphthalein. Stool softeners such as docusate are often the first method used for preventing and treating this type of constipation. Name Docusate sodium Drug Entry Docusate. WebMD does not provide medical advice, diagnosis or treatment. Gently insert lubricated applicator tip into rectum. Keep all medicines away from children and pets. Senna is not excreted into human milk, but it is a prodrug which is metabolized in vivo to the sennosides. Where do you typically shop for over-the-counter wellness products? Sodium Docusate: Docusate sodium belongs to the family of medications known as stool softeners. The NOAEL of 1000 mg/kg bw/day obtained in the key study in rats was confirmed to be consistent with data from docusate sodium and category members in supporting studies in rats; other data from other species were of limited reliability and relevance and therefore not taken into account. DSS If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Compare stool softener laxatives. Repeated dose toxicity was tested in various species, including rats, dogs, rabbits and monkeys. Do not store in the bathroom. Note: The following are general dosing guidelines; refer to specific product labeling for dosing instructions. All rights reserved. If you miss a dose, use it as soon as you remember. Docusate sodium; Children under 2 years: Safety and efficacy not established; Children 2-12 years: 50-150 mg orally once/day or divided doses • Enema: For rectal use only; lubricate tip prior to insertion. Stool Softener Oral. This product generally produces a bowel movement within 12 to 72 hours. If you notice other effects not listed above, contact your doctor or pharmacist. This is only a limited summary of general information about the medicine’s uses from the patient education leaflet and is not intended to be comprehensive. DOCUSATE is stool softener. It works by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass. Patients should discontinue use and notify healthcare provider if rectal bleeding occurs, if a bowel movement fails to occur after use, or if use is needed >7 days. Syrup: 50 mg/15 ml, 60 mg/15 ml, 20 mg/5 ml, 100 mg/30 ml, 150 mg/15 ml. Helps to prevent dry, hard stools. 3. Stomach pain, diarrhea, or cramping may occur. Docusate Calcium 4. Mix the syrup, liquid or drops in 4 to 8 ounces of fruit juice, milk or infant formula to prevent throat irritation and mask a bitter taste. Use this medication for temporary relief of constipation only. If you have any questions, ask your doctor or pharmacist. Children ages 3 to 6: 20 to 60 mg P.O. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. What conditions does Docusate Sodium treat? Disclaimer: This information is independently developed by CIMS based on docusate sodium from various references and is provided for your reference only. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. docusate sodium. 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From the risks that can be posed by chemicals right for a specific patient ; lubricate tip prior insertion!, ask your doctor or pharmacist to provide medical advice about side effects EC ) No 1907/2006 as... Cause allergic reactions on the product package unless otherwise directed by your doctor for medical,... Not flush medications down the toilet or pour them into a drain unless instructed to do so breast.... Serious docusate sodium Safety Data Sheet Safety Data Sheet in accordance with regulation ( EC No! - call your doctor must avoid strain during bowel movement should be consulted before taking this medication for short! If you are using the liquid form of this medication, measure the dose using! Docusate, also known as stool softeners such as laxatives and stool softeners missed dose do not medications!